Chronic joint pain is a condition that can make it hard to lose weight. It decreases your mobility and your range of motion, thus affecting the way you move and exercise. Knee pain makes it harder to walk, jog, and squat. Chronic hip pain affects how you move around and bend over at the waist. Shoulder pain makes it difficult to lift objects. These ailments will impact how you do everyday activities, your fitness level, and ultimately, your weight.